# Swinging Vitamin D Levels Linked to Muscle Loss in Older Patients

*EXPRESS: Vitamin D variability might be linked to sarcopenia, especially with decreased muscle mass in older patients: a retrospective longitudinal study.*

- **Evidence Level**: Preliminary
- **Why this grade**: Retrospective single-clinic review of 215 older patients with borderline odds ratios, and subgroup findings lost significance after correction.
- **Facts**: Duration: 21 months
- **Publication Types**: Journal Article
- **Journal**: Journal of investigative medicine : the official publication of the American Federation for Clinical Research
- **Sample Size**: 215 patients aged 65+ at a geriatric clinic
- **Authors**: Cicek O, Akkar I, Turgut ZI, Yilmaz Kars M, Dogan MH, Tosun Y, Kizilarslanoglu MC
- **Graded and published**: 2026-09-21
- **Last edited**: 2026-09-23
- **Topics**: vitamin D, sarcopenia, muscle
- **DOI**: https://doi.org/10.1177/10815589261493463
- **Original Source**: https://pubmed.ncbi.nlm.nih.gov/42768432/

## Summary

Older patients whose vitamin D levels bounced around a lot over repeated tests were more likely to have sarcopenia, the age-related loss of muscle. Researchers looked back at records of 215 clinic patients aged 65 and up with at least two vitamin D readings. The hint here is that steady levels may matter more than one good reading. The link was weak, the study only looked backwards, and subgroup results faded after stricter statistical checks.

## Practical Takeaway

This study suggests repeated vitamin D checks may tell more than a single measurement in older adults.

---

_Canonical: https://longevity-germany.com/en/research/swinging-vitamin-d-levels-linked-to-muscle-loss-in-older-patients · Part of Longevity Cities · Updated 2026-09-23_