# Weak Grip Strength Linked to Higher Heart Failure Risk, Especially in Women

*Sarcopenia and Its Associated Metabolic Profile Predict Incident Heart Failure: A Prospective Cohort Study of 267 335 Adults in the UK Biobank.*

- **Evidence Level**: Strong
- **Publication Types**: Journal Article
- **Journal**: Journal of the American Heart Association
- **Sample Size**: 267,335 adults without heart failure (avg age 56)
- **Authors**: Zhong Z, Chen Y, Xiang Q, Liu H, Zhao M, Pekovic-Vaughan V, Sund R, Sankaranarayanan R, Cuthbertson DJ, Isanejad M
- **Published**: 2026-07-17
- **Topics**: muscle health, heart failure, sarcopenia
- **DOI**: https://doi.org/10.1161/JAHA.125.047621
- **Original Source**: https://pubmed.ncbi.nlm.nih.gov/42466482/

## Summary

A weak handgrip and muscle loss were tied to a much higher chance of developing heart failure years later. This link was tracked in over 267,000 middle-aged British adults, and it was stronger in younger people and women. The researchers also found that people with muscle loss had blood markers pointing to inflammation and lower omega-3 levels.

## Practical Takeaway

This study suggests keeping muscle and grip strength up may matter for long-term heart health.

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_Canonical: https://longevity-germany.com/en/research/weak-grip-strength-linked-to-higher-heart-failure-risk-especially-in-women · Part of Longevity Cities · Updated 2026-07-17_