# Your Epigenetic Age May Predict How Well Your Body Holds Up as You Age

*Accelerated Epigenetic and Inflammatory Aging and Intrinsic Capacity.*

- **Evidence Level**: Moderate
- **Publication Types**: Journal Article
- **Journal**: JAMA network open
- **Sample Size**: 970 adults aged 20+ (median age 64)
- **Authors**: Rouch L, De Souto Barreto P, Rolland Y, Guyonnet S, Cestac P, Lu WH, Lemaitre JM, Bensadoun P, Furman D, Vellas B, Andrieu S
- **Published**: 2026-07-01
- **Topics**: epigenetic aging, biomarkers, healthspan
- **DOI**: https://doi.org/10.1001/jamanetworkopen.2026.24102
- **Original Source**: https://pubmed.ncbi.nlm.nih.gov/42475093/

## Summary

Scientists tracked people whose biological age was running faster than their birthday age. Those with faster epigenetic aging had weaker overall body and mind function, especially in movement. This effect grew stronger with older age and was more noticeable in men. Inflammation-based aging also mattered, but less so.

## Practical Takeaway

This study suggests epigenetic aging clocks may help spot people at higher risk of functional decline.

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