Exercise Linked to Younger Biological Age, But Effect Is Modest
This study suggests staying physically active may be associated with a slightly younger biological age on certain epigenetic clocks.
Pulling together 44 studies on nearly 145,000 people, researchers found that more physical activity is tied to a younger biological age, but only on certain epigenetic clocks. The effect showed up clearly on GrimAge and Horvath clocks, but not on Hannum or PhenoAge. The size of the benefit was small, and most data came from snapshot studies, so we can't say exercise actually causes the slowdown yet.
Conflict of Interest Disclosure: One author co-founded a longevity medicine clinic and sits on biomarker and longevity boards. Other authors report no conflicts.
Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.
Related Studies
All researchMetformin Added Nothing to Diet and Exercise for Older Adults' Strength
Metformin has a big fan club in longevity circles, but this trial puts a dent in the hype.
A 9-Year Mailed Exercise Program Barely Moved the Needle in Older Women
Nearly 50,000 women aged 66 to 99 were randomly assigned to a long-running, remotely delivered program that encouraged more movement and…
NR May Slow Muscle Aging Clocks While Hard Interval Training Speeds Some Up
Nicotinamide riboside, a popular NAD+ booster, was linked to slower epigenetic aging in muscle across several aging clocks.
