Life Summit Berlin 2026: Speakers and What to Expect (May 29–30)

Berlin. May 29 to 30, 2026. Two days, more than 3,000 attendees, and over 120 speakers from across the longevity world. That is the Life Summit, and this year's lineup looks like a wishlist for anyone who actually reads the research papers.

If you have ever wondered what a longevity conference looks like when it stops pretending and gets serious about evidence, this is it. The list of speakers reads like a who-is-who of the field. And as partners of the event this year, we at Longevity Germany are biased, but we are also genuinely excited about it.

What is the Life Summit, exactly?

The Life Summit is one of Germany's biggest longevity conferences, hosted at the Estrel Berlin during what the organizers call Longevity Week. The 2026 edition is the second outing, following a packed first run in 2025.

This time, it is bigger. Around 3,000 attendees, 120+ speakers, plus exhibitors, masterclasses, and live tests. You get the science talks. You get hands-on biohacking experiences. And you get the kind of hallway conversations that usually only happen at much smaller, invite-only retreats.

The format is B2B & B2C, which means two audiences in one room:

• B2B: investors, biotech founders, clinicians, researchers
• B2C: practitioners, biohackers, longevity-curious people who want better protocols for their own lives

Most of the keynotes work for both. That is part of what makes the event work.

Who is speaking and why does this lineup matter?

Most longevity events recycle the same five names. This one does not. Here are the speakers we are most excited about.

Matt Kaeberlein

If aging research had a Mount Rushmore, Kaeberlein would be on it. He is co-founder of Optispan and the Dog Aging Project, a longtime aging researcher at the University of Washington, and has published more than 200 papers on the biology of aging. His work on rapamycin (a drug that, in mice, extends lifespan by up to 25% depending on dose and protocol) put a real, testable intervention on the longevity map.

Why he matters: Kaeberlein cuts through hype. When supplement brands or influencers overclaim, he calls it out publicly. He is also one of the most data-driven voices on what actually works in 2026, and what is still pure speculation.

Aubrey de Grey

The original. De Grey has been arguing for longevity escape velocity (the idea that medicine could one day add more than a year of healthy life every year, faster than you age) for over two decades. In 2007, this sounded like science fiction. In 2026, it is a serious research direction at the LEV Foundation, where he is President and Chief Science Officer.

He still wears the long beard. He still talks about the seven types of cellular damage that drive aging. And his recent appearances alongside Kaeberlein, who used to be openly skeptical of his work, have become some of the most interesting conversations in the field.

Bas Kast

German readers know him already. Kast is the science journalist behind "Der Ernährungskompass" (The Diet Compass), the bestselling book that translated decades of nutrition research into rules a normal human could follow.

His angle is unusual. He came to longevity through fear: in his 40s, he had a heart scare, dug into the research, and came out the other side with one of the most readable summaries of what to eat (and what not to) ever published in German. Worth listening to even if you have heard the basics.

Dr. med. Lutz Graumann

Sports physician and performance coach with a strong following in the German longevity space. Expect content on Zone 2 cardio (training at a pace where you can still hold a full conversation), VO2 max (the maximum amount of oxygen your body uses during hard exercise), and recovery.

Simone Koch

A German functional medicine doctor with a focus on hormones and personalized preventive care. Koch is one of the few voices in the German-speaking space who treats women's longevity as its own science rather than a footnote to male-focused research.

Mirela Mus and Maya Fehling (The Longevity Practice)

The duo behind The Longevity Practice in Berlin, one of the city's better-known longevity clinics. Together they pair clinical care with operational rigor.

Filippo Nigro (YOU(th) Health Tech)

Co-founder and CEO of YOU(th) Health Tech, the Munich-based startup that just raised $4.5M to turn your smartphone into a preventive screening tool. The platform analyzes face videos, voice, eye photos, skin images, typing patterns, and step data to estimate 50+ digital biomarkers in under two minutes. Things like heart, lung, metabolic, cognitive, and skin signals, with no needles or clinic visits.

Dr. med. Jonathan Apasu (Adon Health)

Physician and co-founder of Adon Health in Munich. Adon is a digital men's health platform that started with testosterone replacement therapy and is expanding into broader preventive care. Founded in late 2023 with Maximilian Schubert, both former McKinsey, the company raised a high six-figure pre-seed in 2024 led by Backbone Ventures.

Apasu is also one of the more thoughtful voices on the men's health side of longevity. He hosts the German-language Männergesundheit podcast and recently appeared in NZZ's documentary "Testosteronboom: Medizin oder Geschäft?"

What does the science actually say in 2026?

A fair question if this is your first conference.

Here is the short version. The evidence base for extending healthspan (the years you live in good health, not just total years) has gotten much stronger in the last five years. A few examples of what speakers will likely reference.

Strength training. A 2022 meta-analysis in the American Journal of Preventive Medicine found that any amount of resistance training was linked to a 15% lower risk of all-cause mortality compared with doing none. The largest reduction (around 27%) showed up at roughly 60 minutes per week, with diminishing returns above that. So you do not need to live in the gym. You need to show up.

VO2 max. A 2018 study in JAMA Network Open followed 122,007 patients undergoing treadmill testing at the Cleveland Clinic. People with elite cardiorespiratory fitness (roughly the top 2.5%) had about an 80% lower risk of dying than the lowest performers. Translation: a 5x difference. The authors found no upper limit on the benefit, which means more fitness keeps helping, all the way up.

Sleep. A 2024 study in QJM: An International Journal of Medicine followed 172,321 adults and found that those with all five healthy sleep habits gained an extra 4.7 years of life expectancy at age 30 for men and 2.4 years for women, compared with those who had none or just one.

Social connection. A 2010 PLoS Medicine meta-analysis of 308,849 people found a 50% greater likelihood of survival in those with strong social relationships. The effect was comparable to quitting smoking, and exceeded obesity and physical inactivity as a risk factor.

Most of the speakers at the Life Summit will reference data like this. The point of going is not to hear the headline numbers for the first time. It is to watch the experts argue with each other about what to actually do with them.

Why Berlin?

Five years ago, the European longevity scene barely existed outside a few Swiss clinics. Today, Berlin has become one of its main hubs.

A few reasons:

• The city has a deep biotech and healthtech startup base
• Clinics like The Longevity Practice and YEARS have set up shop here
• German consumers have started paying attention to evidence-based health

Add the fact that Germany still has one of the strongest scientific publishing traditions in Europe, and Berlin makes sense as the host city. It is not Silicon Valley hype. It is closer to clinical, careful, and curious.

Where does the night go after the talks end?

The Life Summit days end at 6 or 7 PM. The conversations don't.

For the night of Day 1, Longevity Germany is hosting an after-drinks event on the rooftop terrace of Baret in Berlin. Mocktails, alcohol-free options, snacks, and the people you actually want to talk to, without the noise of a 3,000-person hall.

The details:

• Date: Friday, 29 May 2026
• Time: 8:00 PM
• Venue: Baret rooftop terrace, Berlin
• Sign up: luma.com/pq47mf21

Spots are limited and approval is required, so registering early helps.

Who is this conference for?

Three groups will get the most out of it:

1. People building in longevity: founders, clinicians, investors. Two days of relevant exhibitors and direct access to operators is hard to find anywhere else in Europe.
2. Practitioners: doctors, nutritionists, coaches who want to update their toolkit with evidence rather than Instagram trends.
3. Curious individuals: anyone who has read Outlive by Peter Attia, listened to enough Andrew Huberman, and now wants to see the real researchers in person without watching another podcast clip.

If you are in any of those buckets, the math is simple. Two days, the people you have been reading, and direct access at the after-events.

A final thought

The Life Summit is one of those events where the value is not just the stage. It is the side conversations, the questions you ask Aubrey de Grey at the coffee station, the offhand comment from Kaeberlein that changes how you think about a study.