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Journal ArticleNature communications·May 2026

A Tiny RNA Fragment May Be Key to How Fasting Extends Lifespan

Scientists found that an enzyme called DIS3 chops transfer RNAs into small pieces that help slow aging. In worms, one fragment called 5'-tRH-Gln was needed for the lifespan boost from dietary restriction. The same system delayed cell aging in mammalian cells, pointing to a shared longevity mechanism across species.

Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.