Epigenetic Clocks Predicted Who Lived to 90, But Not Who Stayed Sharp
Graded Moderate — prospective cohort of 5,844 older women followed to age 90 or death, yet observational and limited to women in a single US study.
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- Participants
- 5,844
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This study suggests epigenetic age tests say little about your future brain health.
Epigenetic clocks are sold as a readout of how fast you're aging. In nearly 6,000 older women tracked for decades, the newer clocks like GrimAge and DunedinPACE did predict who reached 90. But none of the 15 clocks could tell apart women who reached 90 with intact thinking from those who reached 90 with dementia. So a good clock score says something about lifespan odds, not brain health.
Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.