Epigenetic Clocks Predicted Who Lived to 90, But Not Who Stayed Sharp
- Design
- —
- Participants
- 5,844
- Duration
- —
- Funding
- —
This study suggests epigenetic age tests say little about your future brain health.
Epigenetic clocks are sold as a readout of how fast you're aging. In nearly 6,000 older women tracked for decades, the newer clocks like GrimAge and DunedinPACE did predict who reached 90. But none of the 15 clocks could tell apart women who reached 90 with intact thinking from those who reached 90 with dementia. So a good clock score says something about lifespan odds, not brain health.
Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.
Related Studies
All researchYour Epigenetic Age May Predict How Fast Your Grip and Memory Fade
Among about 4,000 older Americans followed for up to 12 years, those whose DNA looked biologically older lost function faster.
Vitamin D3 Plus DHA Beat Either Alone for Memory in Older Adults With MCI
Older adults with mild cognitive impairment took vitamin D3, DHA (an omega-3 fat), both, or a placebo for a year.
Creatine Built Muscle in Midlife Adults Even Without a Single Workout
Adults aged 45 to 65 took 10 grams of creatine daily for 12 weeks, either alone or alongside exercise and a weight-loss diet.