Nicotinamide Riboside May Shield Female Mouse Muscle From Heat Damage
Graded Preliminary — ten-day controlled study in young female mice given oral NR before a single heat exposure, with no data in people yet.
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- Participants
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This early mouse study suggests NR may protect muscle from heat stress, but human data is lacking.
Heat stress can hurt muscle by triggering inflammation and damaging the cell's power plants. In female mice, the NAD+ booster nicotinamide riboside reduced that heat damage, calming inflammation and protecting mitochondria. Curiously, it worked without raising muscle NAD+ levels, so the benefit came through other paths.
Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.
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