Journal ArticleAntioxidants (Basel, Switzerland)·Jul 2026
PQQ Sharpened Memory in Old Mice by Rebooting Brain Cell Batteries
Key Insight
This early animal work suggests PQQ may support brain energy metabolism, but human data is still missing.
PQQ is a supplement often sold for mitochondrial support, and this study gives that claim some backing. Old mice given PQQ did better on memory tests and kept their hippocampal neurons in better shape. In lab-grown brain cells, PQQ cut oxidative stress and boosted the cells' energy output. The effect seemed to run through SIRT1, a protein tied to longevity pathways. This was mice and cells, not people.
Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.
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