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Journal ArticleDiabetes, obesity & metabolism·Jun 2026

Tirzepatide Works Just as Well and as Safely for Adults Over 65

Key Insight

This analysis suggests tirzepatide may be a reasonable weight option for older adults after weighing risks.


Tirzepatide is the popular GLP-1 weight loss drug also sold as Mounjaro and Zepbound. This look back at big trials found it helped adults over 65 lose weight and improve heart and blood sugar health. The benefits and side effects matched what younger adults saw, with no new risks for older bodies.

Conflict of Interest Disclosure: Tirzepatide is made by Eli Lilly, which runs the SURMOUNT and SUMMIT trials.

Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.