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Journal ArticleReviewJournal of molecular neuroscience : MN·May 2026

Why Alzheimer's May Look Like a Viral Infection That Isn't There

This review proposes that Alzheimer's behaves like the brain fighting a fake viral infection. Old retrotransposons and leaked mitochondrial DNA trick immune cells into thinking there's a virus, triggering chronic inflammation and turning brain support cells into zombie-like senescent cells. The authors suggest that HIV drugs (NRTIs) and senolytics could one day target this hidden cascade. It's a fresh angle after years of failed amyloid-focused drugs.

Conflict of Interest Disclosure: Authors declare no competing interests.

Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.