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Journal ArticleReviewnpj aging·May 2026

Why Your Mitochondria May Be Driving Aging and Chronic Inflammation

Key Insight

This review suggests strategies that support mitochondrial health may matter for healthy aging.


Scientists are zeroing in on mitochondria (the energy factories in your cells) as a main driver of aging, not just a casualty of it. When they break down, they leak signals that trigger chronic, low-grade inflammation and exhaust stem cells. This review highlights NAD+ depletion as a key bottleneck and looks at fixes like NAD+ boosters and mitophagy enhancers.

Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.