A Single Protein's Decline in Immune Cells May Drive Body-Wide Aging
Graded Preliminary — mouse study with conditional knockout models and lab cell experiments, with no human data yet, so effects in people remain untested.
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- National Natural Science Foundation of China (National Science Foundation of…
In mice, a protein called Lamtor5 drops with age and lets immune cells called macrophages go into a worn-out, inflammatory state. When scientists put these aged immune cells into young mice, the young mice aged faster. Clearing out the old cells or blocking the harmful pathway calmed inflammation and helped tissues work better. This adds to the idea that aging immune cells fuel the low-grade inflammation behind many age-related problems.
Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.